Exelixis issued a press release on July 28, 2025, "report[ing] financial results for the second quarter of 2025" and "provid[ing] an update on progress toward achieving key corporate objectives, and outlined its commercial, clinical and pipeline development milestones." Among other items, Exelixis reported that net product revenues for cabozantinib were approximately 2% below the consensus estimate of $531.3 million. Exelixis also disclosed that "[b]ased on our evaluation of emerging data from the phase 2 portion of the STELLAR-305 study in advanced squamous cell carcinoma of the head and neck, emerging competition in this indication and assessment of other potentially larger commercial opportunities, we have made the decision not to proceed to the phase 3 portion of the trial."
Following this news, Exelixis's stock price fell over 16% on July 29, 2025.
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